Radhika Jones, editor in chief of Vanity Fair, is among the event's honorees.
Adam Duritz and David Immerglück of Counting Crows will perform at the Nov. 8 event.
Counting Crows and Katharine McPhee are also set to perform.
Sheryl Lee Ralph will receive the inaugural Sheryl Lee Ralph Legacy Award.
The award will be presented at the 43rd annual John Lennon Tribute on Dec. 2 at Town Hall in New York.
The late philanthropist and wife of music industry legend Clarence Avant "was a collector of souls who wanted to make sure everyone got the chance to fly."
The Nashville-based cancer charity rebounds after a former executive was found guilty of embezzling $4 million from the organization.
The money, which will be donated over the next five years, marks the largest single donation in the foundation's history.
